Highlights
Human IPSC-Derived PreBötC-Like Neurons and Development of an Opiate Overdose and Recovery Model, published in 2023 by Hesperos in Advanced Biology, has been recognized as a top viewed article in the journal.
The study describes the development of Hesperos' opioid overdose and recovery model using human preBötC neurons from induced pluripotent cells (iPSCs)
This iPSC-preBötC mimic is needed for researching opioid-induced respiratory depression (OIRD) and was the first step in the integration of a functional overdose model into microphysiological systems
This was a crucial development in mitigating the widespread opioid crisis