The Original Human-on-a-Chip Company

Pioneers for Reducing Animal Testing through Emulating Biology

the leading light for human-on-a-chip Research

Hesperos is named for Venus in the evening sky. Like her, we are a leading light, providing world-class research in disease modeling and drug testing through our use of human-on-a-chip systems. Our patent positions and the over 20 years of expertise of both Drs. Shuler and Hickman make us the company to work with for your most difficult problems as well as for cost competitive, routine, human-on-a-chip assays.

The hesperos difference

Hesperos, Inc. brings together biologists, surface chemists, and engineers in order to produce some of the worlds most advanced organs-on-chips. From gene expression to electrophysiology, our biologists recreate key components of various organs. Chemically patterned microchips are engineered to enable real-time monitoring of organ activity. Finally, our engineers utilize sophisticated measurement techniques in order to detect and quantify minute changes.  The result of this collaboration is an ability to study therapeutics in a way which was previously only possible in clinical trials.

As Featured In

Industries We Serve

Rare Disease

Pharmacology

Chemicals, Nutraceuticals, and Supplements

Hesperos demonstrates innovative Human-on-a-Chip® approach to modeling innate immune system response following tissue damage and acute inflammation

By Hesperos | June 2, 2020

— New publication in Advanced Science validates potential use in evaluating certain immune responses in drug discovery and systemic diseases, including Coronavirus Disease 2019 (COVID-19)— — Hesperos’ immune system-on-a-chip features recirculating immune cells with the key … Read More

Hesperos Human-on-a-Chip® system used to model preclinical stages of Alzheimer’s disease and mild cognitive impairment

By Hesperos | May 28, 2020

— Peer-reviewed publication in Alzheimer’s & Dementia: Translational Research & Clinical Interventions validates potential of drug discovery platform and ability to study early stages of disease pathology — ORLANDO, Fla. – May 28, 2020 – Hesperos … Read More

Discussion of Human-on-a-chip for Rare Diseases

By Hesperos | November 30, 2019

In our latest publication, UCF & Hesperos researchers discuss how Human-on-a-chip systems can be used to address the unique challenges facing rare diseases. Researchers cite that rare diseases are “limited by the high cost of research … Read More

HESPEROS TECHNOLOGY FEATURED ON NIH DIRECTOR’S BLOG: BODY-ON-A-CHIP DEVICE PREDICTS CANCER DRUG RESPONSES

By Hesperos | September 30, 2019

We are proud to announce our latest papers has been featured on the director’s blog of the The National Institutes of Health. In the post, Dr. Francis Collins discusses a study in which Hesperos created a … Read More

Hesperos Human-on-a-Chip Technology Awarded First Phase of $3.8 Million Milestone-based NIH Grant to Study Opiate Overdoses in Collaboration With UCF

By Hesperos | September 26, 2019

Hesperos, Inc., (www.hesperosinc.com) announced today the University of Central Florida (UCF) received the first phase of a $3.8 million milestone-based National Institutes of Health (NIH) grant for research involving the company’s human-on-a-chip system. “We are grateful … Read More

About Our Team

Hesperos, Inc, is a leader in efforts to characterize an individual’s biology with human-on-a-chip microfluidic systems. Founders Michael L. Shuler and James J. Hickman have been at the forefront of every major scientific discovery in this realm, from individual organ-on-a-chip constructs to fully functional, interconnected multi-organ systems which they coined "human-on-a-chip."

Simulating Organ Function

Unlike other tests that extrapolate organ function based on biomarker activity and protein analysis, our models are working systems that recreate muscle and tissue function as well as neural and inter-organ communication. The resulting functional reports closely correlate to what clinicians observe in human clinical trials.

Data Driven Analysis

Our systems generate thousands of data points which correlate to key functional aspects of each organ.  Our custom analyses are then able to parse the data quickly and fruitfully to identify subtle changes in function alongside large-scale shifts in morphology and behavior, yielding insights into each drug.

Interested in working with hesperos?