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Microphysiological Systems as Applied for Rare Diseases Therapeutic Development

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Hesperos Chief Scientist Dr. J Hickman was a featured speaker at NIH Rare Disease Day, covering how Human-on-a-chip systems are supporting rare diease therapuetics.  His talk, titled "Rare Story #3: Microphysiological Systems as Applied for Rare Diseases Therapeutic Development," presented Hesperos's commerically available models and how they have been used to test the efficacy of new pharmaceuticals.

NIH Rare Disease Day brought speakers from Congress, the FDA, Industry, Academia, and patient advocates together to discuss ways to accelerate development of new therapeutics for this underserved population.  View Dr. Hickman's talk below or

Click here to watch the full conference on NIH.gov

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Development of a Malaria-on-a-Chip Model doi.org/10.1038/s41598-023-35694-4 Model developed to study Malaria and potential therapeutics Press Release Link to Publication Hesperos scientists have published a groundbreaking study in Scientific Reports, a Nature journal. The publication, titled “Development … Read More

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Read the Open Letter here We are proud to support this open letter to congress encouraging representatives to pass the FDA Modernization Act.  Originally passed in 1938, the Federal Food, Drug, and Cosmetics Act (FFDCA) was … Read More

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1) Validates use of Human-on-a-Chip system to mimic disease mechanisms of rare autoimmune neuropathies that cannot be replicated in animal models.

2) Efficacy data from microphysiological system supported the authorization of a clinical study (NCT04658472) in 2021 through collaboration with Sanofi.

Using Human-on-a-Chip technology to reduce animal testing in drug discovery
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Senior Editor with Pharma Manufacturing interviews Hesperos executives Michael Shuler and Nathan Post on the rise of Human-on-a-Chip (HoaC) systems and how they are replacing the need for animal testing in drug discovery.