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X-WR-CALDESC:Events for Hesperos Inc.
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BEGIN:VEVENT
DTSTART;TZID=UTC:20250902T130000
DTEND;TZID=UTC:20250902T143000
DTSTAMP:20260427T113308
CREATED:20250829T195357Z
LAST-MODIFIED:20250829T195357Z
UID:3201-1756818000-1756823400@hesperosinc.com
SUMMARY:WC13 2025: Hesperos CEO Presents "Utilization of human on a chip systems for rare disease regulatory submissions"
DESCRIPTION:Track:  Accelerating rare disease therapeutics via adoption of human biology-based non-clinical drug development in global north and global south countries\nHuman Health – Replacement \nSession Chair \nJanette Turner – Humane World for Animals\n\nSession Speakers \n\nAbstract 553\nUtilization of human on a chip systems for rare disease regulatory submissions\nLawrence Florin\, Hesperos\, Inc.\nAbstract 323\nModelling cardiac arrhythmias with human induced pluripotent stem cells\nAntonio Carvalho\, Federal Univ. Rio de Janeiro\nAbstract 459\nMultiparametric screening of MASH clinical candidates in human liver spheroids predicts clinical outcomes and reveals potential novel combinations for anti-steatotic and anti-fibrotic therapies.\nMadhu Lal-Nag\, https://insphero.com/\nAbstract 464\nAccelerating the development of Complex In Vitro Models (CIVMs) for rare disease therapeutics in India\nFrancesca Pistollato\, Humane World for Animals Europe\n\n\nSession Description\nRare diseases represent a significant disease burden and impact up to 10% of the world’s population. In particular\, south Asian countries experience higher rates of rare genetic disorders which has been attributed to traditional marriage practices of endogamy and consanguinity. Despite this\, there are no approved treatments for almost 95% of rare diseases. While the use of genetically engineered animal models is traditionally considered as one of the main strategies for rare disease therapeutics\, these model systems have often proven unsuitable for providing human-relevant insights into the patho-mechanisms of rare diseases. Recently\, efficacy data from a microphysiological system developed using human cells were used to support the authorisation of a clinical study for chronic inflammatory demyelinating polyneuropathy\, a rare neuromuscular disease. This\, and several other examples\, highlight the potential of complex in vitro models (CIVMs)\, including induced pluripotent stem cell (iPSCs)\, organoids\, and organs-on-chips\, to provide personalized model systems for understanding the biological mechanisms and assessing drug efficacy for rare diseases. \nThis workshop will include two sessions. The first session will aim to provide a global perspective on the status quo of the use and development of complex in vitro models to support drug development of rare diseases. We will hear from experts from around the world who have successfully used CIVMs to demonstrate drug efficacy and learn more about the challenges faced across different global regions. This would include talks on successful case studies that have used CIVMs to test the efficacy of repurposed drugs and progress to clinical trials\, general overview of how industry is currently using these systems in their internal drug development pipeline for rare diseases. The session would also include two talks from global south country-perspective where the higher cost of rare disease treatments also renders it inaccessible to most of the population\, highlighting the need for his would be followed by a session where it would be discussed how these insights from rare diseases could be used to develop a generalised framework for efficacy testing for other disease categories. We hope to develop a white/status paper covering the recommendations that emerge from these sessions. \nSession organization (90 minutes) \nSession 1: Human preclinical models for rare disease therapeutics- Status quo and challenges (45 minutes)\n1. Introduction– How CIVMs can provide a personalized system for efficacy testing\, general statement of needs or challenges (Suggested Speaker: James Hickman\, Hesperos Inc. – we have reached out to Dr Hickman and he has shown interest\, yet to accept)\n2. Case study – Developing efficacy models for cystic fibrosis using lung-on-a-chip (Suggested Speaker: Roberto Plebani\, Emulate. Inc)\n3. Accelerating the development of CIVMs for rare disease therapeutics in India: Not for profit speaker (Suggested speaker: Surat Parvatam\, HSI/India) \nSession 2: Breakout session on developing a generalized framework for incorporating CIVMs for efficacy testing based on insights from rare diseases (45 minutes)\nThis breakout session will focus on discussions on how strategies and insights from efficacy modelling for rare diseases can assist in creating a generalised framework for incorporating CIVMs into efficacy modelling of other disease models.
URL:https://hesperosinc.com/event/wc13-2025-hesperos-ceo-presents-utilization-of-human-on-a-chip-systems-for-rare-disease-regulatory-submissions/
LOCATION:Riocentro Convention Center\, Av. Salvador Allende\, 6555 - Barra Olímpica\, Rio de Janeiro\, Brazil
CATEGORIES:Invited Speaker
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2025/08/Screenshot-2025-08-29-135151.jpg
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BEGIN:VEVENT
DTSTART;TZID=UTC:20250904T110000
DTEND;TZID=UTC:20250904T120000
DTSTAMP:20260427T113308
CREATED:20250829T193950Z
LAST-MODIFIED:20250829T194326Z
UID:3199-1756983600-1756987200@hesperosinc.com
SUMMARY:Webinar:  Insights Without Animals: Leveraging Human-on-a-Chip & PBPK Modeling
DESCRIPTION:Summary\nThe pharmaceutical industry is transitioning away from animal tests\, per the recent FDA Roadmap. Scientists’ need for drug development insights without animals has spurred greater interest in New Approach Methodologies (NAMs)\, such as in silico modeling and in vitro assays like organ-on-a-chip. \nThis webinar will explore how Human-on-a-Chip (HoaC) systems—combined with physiologically-based pharmacokinetic (PBPK) modeling—enable a powerful\, human-relevant approach to predicting safety and efficacy in drug development. Speakers will showcase how HoaC data can be translated into in vivo outcomes using biosimulation\, with case studies illustrating regulatory and program-level impact. \nWho should attend: \nR&D and translational leaders in biotech and pharma\nToxicologists and DMPK scientists\nClinical pharmacologists and regulatory professionals\nModeling & simulation experts \nClick here to register
URL:https://hesperosinc.com/event/webinar-insights-without-animals-leveraging-human-on-a-chip-pbpk-modeling/
LOCATION:Virtual
CATEGORIES:Webinar
ATTACH;FMTTYPE=image/png:https://hesperosinc.com/wp-content/uploads/2025/08/Screenshot-2025-08-29-134250.png
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20250917
DTEND;VALUE=DATE:20250918
DTSTAMP:20260427T113308
CREATED:20250717T181110Z
LAST-MODIFIED:20250717T181110Z
UID:3178-1758067200-1758153599@hesperosinc.com
SUMMARY:Labroots Cell Biology Virtual Events Series 2025
DESCRIPTION:Labroots Cell Biology Virtual Events Series 2025\nInvited Speaker \nChristopher Long\, PhD \nSept. 17th\, on demand all day \nAbout the Labroots Cell Biology Virtual Event Series:  This virtual event provides a place for interdisciplinary exchange and knowledge-sharing opportunities.  Leading experts\, researchers\, and innovators will share breakthroughs and discuss the latest trends and methodologies in cell biology. \nRegister free to watch Dr. Long’s presentation at https://www.labroots.com/virtual-event/cell-biology-2025
URL:https://hesperosinc.com/event/labroots-cell-biology-virtual-events-series-2025/
LOCATION:Virtual
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2025/07/virtual_event_header_banner_image_c1b61b6e123bfc85a6861c6cb80fc78786ff698f_5153.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20250922
DTEND;VALUE=DATE:20250926
DTSTAMP:20260427T113308
CREATED:20250609T154351Z
LAST-MODIFIED:20250610T130827Z
UID:3124-1758499200-1758844799@hesperosinc.com
SUMMARY:23rd Annual Discovery on Target
DESCRIPTION:23rd Annual Discovery on Target\nSept. 22-25 \nInvited Speaker  \nJames Hickman\, PhD\, Hesperos Co-Founder and Chief Scientist \nRegulatory Acceptance of Human-on-a-Chip Platforms \nSept. 22\, 9:00 AM EST \nAbout Discovery on Target: This week long event in Boston\, MA showcases the latest research on current and emerging drug targets and technology.  There will be numerous presentations\, discussions\, and networking opportunities for those at the forefront of drug discovery. \nLearn more and register at https://www.discoveryontarget.com/
URL:https://hesperosinc.com/event/23rd-annual-discovery-on-target/
LOCATION:Sheraton Boston
CATEGORIES:Invited Speaker
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2025/06/DOT-banner-LI-standard-speaking-at-code.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20251205
DTEND;VALUE=DATE:20251206
DTSTAMP:20260427T113308
CREATED:20251107T215334Z
LAST-MODIFIED:20251110T164829Z
UID:3363-1764892800-1764979199@hesperosinc.com
SUMMARY:The 3Rs Collaborative & IQ-Consortium: Microphysiological Systems Webinar & Workshop Series
DESCRIPTION:Webinar: Microphysiological Systems Webinar & Workshop Series\nWednesday\, December 3\, 2025\n10 am-12:30 p.m. (EST)\nInvited Speaker\nJ Hickman\, PhD\, Chief Scientist \n  \nAbout the webinar: 3RsC MPS in Drug Development program is an initiative by The 3Rs Collaborative (3RsC) to advance the adoption and regulatory acceptance of Microphysiological Systems (MPS) technologies\, in alignment with the principles of the 3Rs (Replacement\, Reduction\, and Refinement) in animal research. 
URL:https://hesperosinc.com/event/the-3rs-collaborative-iq-consortium-microphysiological-systems-webinar-workshop-series/
LOCATION:The Three Rs Collaborative\, United States
CATEGORIES:Invited Speaker,Webinar
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2025/11/Na3rc-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20251205
DTEND;VALUE=DATE:20251206
DTSTAMP:20260427T113308
CREATED:20241212T195120Z
LAST-MODIFIED:20250703T193630Z
UID:2910-1764892800-1764979199@hesperosinc.com
SUMMARY:Hybrid Public Workshop: Pediatric Developmental Safety Assessment and Novel Alternative Methods
DESCRIPTION:Hybrid Public Workshop: Pediatric Developmental Safety Assessment and Novel Alternative Methods \nDec. 5th\, 2025 \nSilver Spring\, MD \nInvited Speaker \nJ Hickman\, PhD\, Chief Scientist \nAbout the Hybrid Public Workshop: Pediatric Developmental Safety Assessment and Novel Alternative Methods:  This free public workshop is organized by the CDER Office of Clinical Pharmacology and Triangle CERSI.  It will cover advances in pediatric drug development programs and New Approach Methodologies (NAMs) being used as alternatives to animal testing in pediatric preclinical assessments.
URL:https://hesperosinc.com/event/pediatric-developmental-safety-assessment-and-novel-alternative-methods/
LOCATION:FDA White Oak Campus
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2024/12/Event-Web-Page-Graphics-49.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20260112T080000
DTEND;TZID=UTC:20260112T170000
DTSTAMP:20260427T113308
CREATED:20260112T014558Z
LAST-MODIFIED:20260112T014558Z
UID:3477-1768204800-1768237200@hesperosinc.com
SUMMARY:2026 - MPS World Summit
DESCRIPTION:Join us! \nMore info coming soon. \nClick here to register: https://mpsworldsummit.org/2026-registration-information/
URL:https://hesperosinc.com/event/2026-mps-world-summit/
LOCATION:Walter E. Washington Convention Center
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2026/01/Screenshot-2026-01-11-184339.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260122
DTEND;VALUE=DATE:20260124
DTSTAMP:20260427T113308
CREATED:20260112T013437Z
LAST-MODIFIED:20260119T182021Z
UID:3463-1769040000-1769212799@hesperosinc.com
SUMMARY:International Conference on Advances in 3D Cell Culture
DESCRIPTION:Invited Speaker\nJames Hickman\, Chief Scientist\, Hesperos Inc. \nPresentation:  Regulatory acceptance of human-on-a-chip systems for efficacy and safety \nJanuary 22-23\, 2026 \nFull Program Agenda\n3DCC26_ProgramAgenda_v2 \nLink to register: https://eventregister.mumbaibiocluster.org/ \n 
URL:https://hesperosinc.com/event/international_conference_advances_3d_cell_culture/
LOCATION:Novotel Dona Sylvia Resort\, Cavelossim Road Mobor\, Cavelossim\, GA\, Goa\, India
CATEGORIES:Invited Speaker
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2026/01/1767447014533-e1768846809456.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20260205T110000
DTEND;TZID=UTC:20260205T120000
DTSTAMP:20260427T113308
CREATED:20260203T171253Z
LAST-MODIFIED:20260203T213343Z
UID:3507-1770289200-1770292800@hesperosinc.com
SUMMARY:Webinar:  Multi-organ human-on-a-chip systems for predicting drug efficacy and toxicity
DESCRIPTION:James J. Hickman\, Chief Scientist at Hesperos\, will be presenting at the upcoming webinar: Multi-organ human-on-a-chip systems for predicting drug efficacy and toxicity. Explore how advanced functional human organ models improve preclinical drug testing and toxicity evaluation. \nA major challenge in drug discovery and toxicology is the gap between cell-level studies and whole-animal or human systems.  Researchers are now creating miniaturized human-on-a-chip systems where human-derived cells connect and function in ways that reflect real tissue and organ behavior\, enabling more accurate evaluation of drug efficacy and safety. \nIn this webinar\, James Hickman will discuss developing advanced multi-organ human-on-a-chip systems that model neural\, muscle\, and cardiac subsystems and how these platforms can inform preclinical decision-making. \nTopics to be covered: \n\nDesign\, fabrication\, and validation of multi-organ human-on-a-chip\nModeling motor\, cognitive\, muscle\, and cardiac functions\nApplications in preclinical drug discovery and toxicity testing\n\nClick HERE to register!
URL:https://hesperosinc.com/event/multi-organ-human-on-a-chip-systems-for-predicting-drug-efficacy-and-toxicity/
LOCATION:Virtual
CATEGORIES:Webinar
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2026/02/DDN-webinar.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260322
DTEND;VALUE=DATE:20260326
DTSTAMP:20260427T113308
CREATED:20260304T195539Z
LAST-MODIFIED:20260320T144307Z
UID:3539-1774137600-1774483199@hesperosinc.com
SUMMARY:Join Hesperos at Society of Toxicology (SOT) 2026: Booth #846
DESCRIPTION:Visit Hesperos at SOT 2026 ToxExpo: Booth #846\nStop by and take the opportunity to discuss how Hesperos’ single and multi-organ Human-on-a-Chip® organ system models can help your organization better elucidate and understand your product’s profile. \n\nFeatured Presentations\n \n\nPoster Presentation: \n#H624: The Utilization of In Vitro\, Human on a Chip Cortical Networks to Assess Neurocognitive Impairment for Drug Safety and Efficacy \n\nPresented by: Rocky Brighton\nTuesday\, March 24\, 9:15am – 11:45am PT\nView Session Details\n\n\nPoster Presentation: \n#F505: Off target toxicity and efficacy testing of a novel stress reliever in a multi-organ microphysiological system \n\nPresented by: Christopher McAleer\, PhD\nWednesday\, March 25\, 9:15am – 11:45am PT\nView Session Details\n\n\n\n\n  \nView Hesperos SOT Booth #846
URL:https://hesperosinc.com/event/hesperos-at-sot-2026-booth-846/
LOCATION:San Diego Convention Center
CATEGORIES:Exhibitor,Poster Presentation
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2026/03/SOT-Announcement-Graphic1200-x-700-px.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260408
DTEND;VALUE=DATE:20260409
DTSTAMP:20260427T113308
CREATED:20260403T171458Z
LAST-MODIFIED:20260403T171546Z
UID:3654-1775606400-1775692799@hesperosinc.com
SUMMARY:Hesperos Chief Scientist Presenting at Quantitative Systems Pharmacology Conference 2026​​​​​​​​​​​​​​​​​​
DESCRIPTION:Details:\nDate: 08 April 2026\nTime:  16:10 (UTC+2)\nSession 4: Integrating Micro-Physiological and Organ-on-Chip Systems with QSP \nHesperos\, Inc. is proud to announce that our Chief Scientist\, Dr. James J. Hickman\, will be a featured speaker at the upcoming Quantitative Systems Pharmacology Conference (QSPC) 2026 in Leiden\, Netherlands. This event brings together global leaders from academia\, industry\, and regulatory agencies to explore advances in quantitative systems pharmacology (QSP) and mechanism-based pharmacokinetics and pharmacodynamics (PK/PD).  \nPresentation:\n“Regulatory Acceptance of Microphysiological and Organ-on-Chip Systems”\nAs the drug discovery landscape shifts toward more human-relevant models\, the integration of microphysiological systems (such as our Human-on-a-Chip® single- and multi-organ system models) with QSP is becoming a critical bridge for translational success. In this talk\, Dr. Hickman will discuss the path toward regulatory acceptance for these platforms. \nSession 4 explores the synergy between organ-on-a-chip platforms and the mathematical frameworks of QSP including PK/PD. Among other topics\, attendees will gain a deeper understanding of: \n\nThe current status of MPS validation for regulatory use.\nHow Hesperos’ serum-free\, single and multi-organ platforms can be combined with QSP models.\nStrategies for utilizing human-relevant data to better inform and accelerate clinical development timelines.\n\nAbout the Speaker\nJames J. Hickman\, Ph.D.\, is the Chief Scientist and Co-Founder of Hesperos\, Inc. He is also the Founding Director of the NanoScience Technology Center at the University of Central Florida. A pioneer in the field\, Dr. Hickman has spent over 30 years developing functional in vitro systems. He is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE)\, the National Academy of Inventors\, and is the President of the International Microphysiological Systems Society (IMPSS). \n\nPlanning to attend QSPC 2026? We invite you to connect with Dr. Hickman to discuss how our Human-on-a-Chip® technology can support your drug development programs. \nLink to Registration and Full Program
URL:https://hesperosinc.com/event/hesperos-chief-scientist-presenting-at-quantitative-systems-pharmacology-conference-2026/
LOCATION:Stadsgehoorzaal\, Breestraat 60\, 2311 CS\, Leiden\, Leiden\, Netherlands
CATEGORIES:Invited Speaker
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2026/04/JH-Talk-QSPC-2026.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260417
DTEND;VALUE=DATE:20260418
DTSTAMP:20260427T113308
CREATED:20260413T172611Z
LAST-MODIFIED:20260413T172611Z
UID:3678-1776384000-1776470399@hesperosinc.com
SUMMARY:Hesperos Presenting at the HNF CMT Summit 2026
DESCRIPTION:Date: 17 April 2026\nTime: 1:50 PM – 2:30 PM (EDT)\nEvent: HNF CMT Summit + Health & Wellness Retreat 2026\nLocation: Ellicott City\, Maryland \nHesperos\, Inc. is proud to announce that our Chief Scientist\, Dr. James J. Hickman\, will be a featured speaker at the upcoming HNF CMT Summit + Health & Wellness Retreat 2026 in Ellicott City\, Maryland. Hosted by the Hereditary Neuropathy Foundation (HNF)\, this event brings together global leaders from academia\, industry\, clinical practice\, and the patient community to explore the latest research and advancements in Charcot-Marie-Tooth (CMT) disease. \nPresentation – Research Track: AI & Technology Advances in CMT \nThe integration of artificial intelligence and microphysiological systems (such as our Human-on-a-Chip® single and multi-organ platform) are becoming a critical bridge for translational success in rare diseases\, including CMT. In this talk\, Dr. Hickman will discuss how these technologies will continue to benefit research and therapeutic development in this and other rare disease arenas. \nHighlights attendees can expect to explore include: \n\nHow artificial intelligence and cutting-edge\, human-relevant in vitro technologies are accelerating drug discovery and target identification for CMT and other rare diseases.\nThe role Hesperos’ serum-free\, multi-organ platforms have played modeling complex neuropathies and supporting therapeutic development\, including an example utilizing sera from an individual patient with CMT2A to evaluate efficacy of a potential therapeutic gaining an Orphan Drug Designation (See March 2025 Announcement).\n\nAbout the Speaker \nJames J. Hickman\, Ph.D.\, is the Chief Scientist and Co-Founder of Hesperos\, Inc. He is also the Founding Director of the NanoScience Technology Center at the University of Central Florida. A pioneer in the field\, Dr. Hickman has spent over 30 years developing functional in vitro systems. He is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE)\, the National Academy of Inventors\, and is the President of the International Microphysiological Systems Society (IMPSS). \nPlanning to attend the CMT Summit 2026? We invite you to connect with Dr. Hickman to discuss how our Human-on-a-Chip® platform technology can support your drug development programs. \nLink to Registration and Full Program \n\n\n 
URL:https://hesperosinc.com/event/cmt-summit-26-invited-talk/
LOCATION:Turf Valley Resort\, 2700 Turf Valley Road\, Ellicott City\, MD\, 21042\, United States
CATEGORIES:Invited Speaker
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2026/04/final-mdt-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20260615
DTEND;VALUE=DATE:20260619
DTSTAMP:20260427T113308
CREATED:20260112T014113Z
LAST-MODIFIED:20260112T225840Z
UID:3471-1781481600-1781827199@hesperosinc.com
SUMMARY:PCRM Summer Immersion on Innovative Approaches in Science
DESCRIPTION:James J. Hickman\, Chief Scientist at Hesperos\, will be presenting at the upcoming Summer Immersion program hosted by Physicians Committee for Responsible Medicine in collaboration with Johns Hopkins Bloomberg School of Public Health. \nThis free\, four-day program focuses on New Approach Methodologies (NAMs)\, including our Human-on-a-Chip® platform\, and their application across basic\, translational\, and regulatory science. \nLearn more and apply here: https://www.pcrm.org/ethical-science/summer-immersion \n \n 
URL:https://hesperosinc.com/event/pcrm-summer-immersion-on-innovative-approaches-in-science/
LOCATION:Johns Hopkins Bloomberg School of Public Health\, Baltimore\, MD\, United States
CATEGORIES:Invited Speaker,Workshop
ATTACH;FMTTYPE=image/jpeg:https://hesperosinc.com/wp-content/uploads/2026/01/2026-Summer-Immersion_Horizontal_Logo.jpg
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